Psoriasis is considered a systemic autoimmune inflammatory condition [4,11], yet no associated antibody has ever been identified. The presence of chemical messengers called cytokines leads to inflammation, causing overgrowth of the skin cells.  Normally, skin cells travel rapidly from the lower layers of the skin to the surface, die and are shed within about 6 weeks.  When these cells cannot be shed quickly enough, they build up, forming the recognisable silvery scaly plaques of the condition.  Psoriasis commonly appears in related people – about one third of sufferers have a family member with it.  [11]